January 27, 2023

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Allergic Contact Dermatitis

What is allergic contact dermatitis?
Allergic contact dermatitis is a type of dermatitis/eczema caused by an allergic reaction to a substance called an allergen that comes in contact with the skin. Allergens are harmless to people without allergies. Allergic contact dermatitis is also known as contact allergy.
Who Has Allergic Contact Dermatitis?
Allergic contact dermatitis is common in the general public and in some occupational groups.
It is more common in women than men, mainly due to nickel and acrylate allergies associated with the latest nail cosmetics.
Many babies are also allergic to nickel.
Contact allergies to topical antibiotics are common in patients over 70 years of age.
Allergic contact dermatitis is particularly common in metalworkers, beauticians, beauticians, medical professionals, cleaners, painters, and florists.
What causes allergic contact dermatitis?
Allergic contact dermatitis is a type 4 or delayed hypersensitivity reaction that occurs 48 to 72 hours after exposure to an allergen. This mechanism involves CD4 + T cells that recognize antigens on the skin’s surface and release cytokines that activate the immune system and cause dermatitis. Note:
Contact allergies arise primarily from skin allergens and not from internal or dietary sources.
Very few people react to a specific allergen and it is harmless for people without allergies.
You could have been in contact with the allergen for years without causing dermatitis.
Contact with small amounts of allergens can cause dermatitis.
Patients with impaired skin barrier function are more susceptible to allergic contact dermatitis. For example, patients with leg ulcers, perianal dermatitis and chronic irritation contact dermatitis.
Patients with atopic dermatitis associated with defects in filaggrin (a structural protein in the stratum corneum) are also at increased risk of developing allergic contact dermatitis.
What are the clinical features of allergic contact dermatitis?
Allergic contact dermatitis occurs several hours after exposure to a problematic substance. As long as the skin is no longer in contact with the allergen, it will wear off after a few days.
Allergic contact dermatitis is most often confined to the area of contact with the allergen, but may spread beyond the area of contact or become systemic.
Finger infections can lead to eyelid and genital dermatitis.
If the area of skin most exposed to the allergen remains intact, the dermatitis is unlikely to be caused by a specific allergen.
Affected skin may be red and itchy, swollen, blistering, or dry and bumpy.
Common examples of allergic contact dermatitis include:
Skin eczema on contact with precious stones due to a contact Skin Allergy Types to nickel
Reaction to the smell of perfumes and household items.